Metabolic and mitochondrial research

About Metabolic and mitochondrial research

This research area brings together peptides and related compounds for studies of energy metabolism and mitochondrial function. MOTS-c is a peptide of 16 amino acids encoded in the mitochondrial genome. SS-31, also called elamipretide, is a tetrapeptide that binds to cardiolipin in the inner mitochondrial membrane. Cagrilintide is a lipidated analogue of amylin, and B7-33 is derived from the B chain of relaxin.

Not every product in this area is a peptide. NAD+ is a coenzyme, AICAR a nucleoside analogue, 5-Amino-1MQ and SLU-PP-332 are small molecules, and methylene blue is a dye. Different rules apply to dissolving and storing them than to peptides. Methylene blue solution should be kept out of the light.

The products come as a lyophilisate, as capsules, as a solution or as a cartridge. Cell-based assays and measurements of the respiratory chain are typical lab applications.

Comparisons and further reading

• Peptide content vs purity: the difference explained
• Storing peptides: fridge, freezer and lyophilisate

Common questions