Peptide glossary · Structure and synthesis
D-amino acid
The mirror image of the natural L-amino acid. Proteases recognise D-amino acids poorly, which is why many synthetic peptides such as GHRP-2 or ipamorelin contain D-residues on purpose.
In the lab
D-amino acids are often written with a leading "D-" or in lower case in sequences. The mass is the same as the L form, but stability against proteases is higher.
Read moreData comparisonMore terms: Structure and synthesis
- AcetylationAdding an acetyl group, usually at the N-terminus.
- Aib (aminoisobutyric acid)A non-proteinogenic amino acid with two methyl groups on the alpha carbon.
- AmidationReplacing the C-terminal carboxyl group with an amide.
- AnalogueA molecule that resembles a natural model but is changed on purpose, for example by swapping amino acids or adding a side chain.
- C-terminusThe end of a peptide with the free carboxyl group, on the right of the sequence.
- Deletion sequenceA synthesis by-product missing one or more amino acids.
For laboratory research use only. Not for use in humans or animals.